Inoculation

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Mary Wortley Montagu, by Charles Jervas , after 1716

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Lady Mary Wortley Montagu watched Ottoman doctors scratch pus into children's arms in 1717 and brought the technique to England the following year — inoculating her own son, then daughter, as living proof of concept.

Sue's skeleton logged gout, healed T. rex bite wounds, and a jawbone rotted through by bacterial infection — a biography of agony written in 67-million-year-old bone.

When New York's legislature sided against him in an 1867 rail dispute, Cornelius Vanderbilt cut all rail connections into Manhattan in January — mid-winter — strangling the city's supply lines until Albany capitulated.

Amelio Robles Ávila rode with Emiliano Zapata's forces through the Mexican Revolution, earning the rank of colonel through combat — then lived openly as a man for eight more decades, receiving veterans' recognition from the Mexican government in his nineties.

Congress approved a supercollider larger than the LHC, dug 23 km of tunnel under Waxahachie, Texas, then cancelled it in 1993 mid-bore — $2 billion already spent, hole still in the ground.

IMF chief Dominique Strauss-Kahn was hauled off an Air France plane at JFK in his underwear, May 2011, accused by hotel maid Nafissatou Diallo of assault — ending the near-certain next presidency of France.

Tod Frye had five weeks to port Pac-Man to the Atari 2600 — constrained to a 4KB cartridge — and shipped a version so degraded that 12 million units moved but consumer trust in Atari never recovered.

The entire world of this 2007 JRPG is the fever dream Frédéric Chopin experienced while dying of tuberculosis in 1849. Every dungeon boss is a real Chopin composition. He narrates his own hallucinated death.

At −35 °C, 17,000 UN troops punched through 120,000 encircling Chinese soldiers over 17 days at Chosin Reservoir. Weapons froze mid-fire. Marines carried their dead rather than leave them. They called the retreat a march.